Tumor Microenvironment session

Purpose: There is increasing evidence for the importance of tumor oxygenation in the development, progression, and response to therapy. Consequently, many techniques have been developed to assess tumor oxygenation, as reviewed extensively . Methods may provide a qualitative impression of oxygenation status or rigorous quantitation. Techniques vary in spatial and temporal resolution and the ability to assess dynamic changes. Some exploit endogenous molecules or physical characteristics, while many apply reporter molecules to interrogate oxygen tension (pO2). This tutorial will focus on magnetic resonance approaches, but place them in the context of competing modalities.